TMX3 Protein (Myc-DYKDDDDK Tag)
Quick Overview for TMX3 Protein (Myc-DYKDDDDK Tag) (ABIN2734663)
Target
See all TMX3 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This TMX3 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human TXNDC10 / TMX3 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Thioredoxin-Related Transmembrane Protein 3 (TMX3) (AA 40-187) protein (His-IF2DI Tag)
TMX3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
Thioredoxin-Related Transmembrane Protein 3 (TMX3) (AA 1-454) protein (GST tag)TMX3 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Thioredoxin-Related Transmembrane Protein 3 (TMX3) (AA 25-195), (Isoform 2) protein (His-SUMO Tag)TMX3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- TMX3 (Thioredoxin-Related Transmembrane Protein 3 (TMX3))
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Alternative Name
- Txndc10,tmx3
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Background
- This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The canonical protein encoded by this gene has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This gene is expressed in many tissues but has its highest expression in heart and skeletal muscle. It is expressed in the retinal neuroepithelium and lens epithelium in the developing murine eye and haploinsufficiency of this gene in humans and zebrafish is associated with microphthalmia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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Molecular Weight
- 51.7 kDa
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NCBI Accession
- NP_061895
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Pathways
- Cell RedoxHomeostasis
Target
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