Ubiquilin 1 Protein (UBQLN1) (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2734885

This Recombinant Ubiquilin 1 protein is expressed in HEK-293 Cells.

Quick Overview for Ubiquilin 1 Protein (UBQLN1) (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2734885)

Target: Ubiquilin 1 (UBQLN1)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 2

Purification tag / Conjugate: This Ubiquilin 1 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human Ubiquilin-1 (UBQLN1) (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Ubiquilin 1 (UBQLN1)

Alternative Name: Ubiquilin-1 (Ubqln1)

Background: This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer&aposs and Parkinson&aposs disease. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 59 kDa

NCBI Accession: NP_444295