Ubiquilin 3 Protein (UBQLN3) (His tag)

Catalog No. ABIN2734887

This Recombinant Ubiquilin 3 protein is produced in Escherichia coli (E. coli).

Quick Overview for Ubiquilin 3 Protein (UBQLN3) (His tag) (ABIN2734887)

Target: Ubiquilin 3 (UBQLN3)

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This Ubiquilin 3 protein is labelled with His tag.

Characteristics:

• Recombinant human Ubiquilin-3 (UBQLN3) (full length, N-term HIS tag) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Ubiquilin 3 (UBQLN3)

Alternative Name: Ubiquilin-3 (Ubqln3)

Background: This gene encodes a ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and are thus thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This gene is specifically expressed in the testis. It has been suggested that this gene may regulate cell-cycle progression during spermatogenesis, however, it has been shown that the ortholgous mouse gene is dispensable for embryonic development and spermatogenesis.

Molecular Weight: 70.7 kDa

NCBI Accession: NP_059509