USP2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
Recombinant USP2 protein expressed in HEK-293 Cells.
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Catalog No. ABIN2735099
$1,112.40
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20 μg
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United States
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Quick Overview for USP2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2735099)
Target
See all USP2 Proteins
USP2
(Ubiquitin Specific Peptidase 2 (USP2))
Protein Type
Recombinant
Origin
Human
Source
HEK-293 Cells
Application
Antibody Production (AbP), Standard (STD)
Purity
> 80 % as determined by SDS-PAGE and Coomassie blue staining
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Protein Characteristics
- Transcript Variant 2
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Purification tag / Conjugate
- This USP2 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human USP2 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Ubiquitin Specific Peptidase 2 (USP2) protein
USP2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant WB, SDS, ELISA, IP
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- USP2 (Ubiquitin Specific Peptidase 2 (USP2))
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Alternative Name
- Usp2
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Background
- This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
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Molecular Weight
- 45.1 kDa
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NCBI Accession
- NP_741994
Target
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