VAV3 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2735200

This Recombinant VAV3 protein is expressed in HEK-293 Cells.

Quick Overview for VAV3 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2735200)

Target: VAV3 (Vav 3 Oncogene (VAV3))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 2

Purification tag / Conjugate: This VAV3 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human VAV3 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: VAV3 (Vav 3 Oncogene (VAV3))

Alternative Name: Vav3

Background: This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molecular Weight: 32.4 kDa

NCBI Accession: NP_001073343

Pathways: Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway