VPS72 Protein (Myc-DYKDDDDK Tag)
Quick Overview for VPS72 Protein (Myc-DYKDDDDK Tag) (ABIN2735434)
Target
See all VPS72 ProteinsProtein Type
Origin
Source
Application
Purity
-
-
Purification tag / Conjugate
- This VPS72 protein is labelled with Myc-DYKDDDDK Tag.
-
Characteristics
-
- Recombinant human VPS72 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!Your project requires further customization? Contact us and discover our custom protein solutions
-
-
-
Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
-
The tag is located at the C-terminal.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 50 μg/mL
-
Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
-
Storage
- -80 °C
-
Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
-
- VPS72 (Vacuolar Protein Sorting 72 Homolog (S. Cerevisiae) (VPS72))
-
Alternative Name
- Vps72
-
Background
- The protein encoded by this gene is a shared subunit of two multi-component complexes, the histone acetyltransferase complex TRRAP/TIP60 as well as the chromatin remodeling SRCAP-containing complex. The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes. This protein may be responsible for binding H2AFZ, which has a role in chromosome segregation. This protein may also have a role in regulating long-term hematopoietic stem cell activity. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
-
Molecular Weight
- 40.4 kDa
-
NCBI Accession
- NP_005988
-
Pathways
- Stem Cell Maintenance
Target
-