C-Type Lectin Domain Family 6, Member A (CLEC6A) (AA 45-209) protein (Fc Tag)
Quick Overview for C-Type Lectin Domain Family 6, Member A (CLEC6A) (AA 45-209) protein (Fc Tag) (ABIN2745635)
Target
See all C-Type Lectin Domain Family 6, Member A (CLEC6A) ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 45-209
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Purification tag / Conjugate
- Fc Tag
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Purpose
- Fc (human):Dectin-2 (mouse) (rec.)
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Cross-Reactivity
- Mouse
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Characteristics
- Mouse dectin-2 (aa 45-209) is fused at the C-terminus to the Fc portion of human IgG1.
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Endotoxin Level
- <0.01EU/μg purified protein (LAL test).
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C-Type Lectin Domain Family 6, Member A (CLEC6A) (AA 1-209) protein (His tag)
custom-made CLEC6A Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
C-Type Lectin Domain Family 6, Member A (CLEC6A) (AA 1-209) protein (His tag)custom-made CLEC6A Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
C-Type Lectin Domain Family 6, Member A (CLEC6A) (Active) protein (His tag)CLEC6A Origin: Mouse Host: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute with 50 μL sterile water.
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Concentration
- 1 mg/mL
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Buffer
- Contains PBS.
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Handling Advice
- After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0.1 % BSA should be used for further dilutions.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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Expiry Date
- 6 months
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- C-Type Lectin Domain Family 6, Member A (CLEC6A)
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Alternative Name
- :Dectin-2
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Background
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C-type Lectin Superfamily Member 10, Dendritic Cell-associated C-type Lectin 2, DC-associated C-type Lectin 2
Dectin-1 and dectin-2 are type II transmembrane proteins of the C-type lectin family. They contain single carbohydrate recognition domains (CRDs) in their extracellular region. Dectin-1 and dectin-2 are expressed in macrophages and dendritic cells. Dectin-1 recognizes beta-glucans with its CRD and signals through its immunoreceptor tyrosine-based activation motif (ITAM)-like motif in the cytoplasmic domain, whereas dectin-2 recognizes alpha-mannans and transduces its signal through association with the ITAM-containing Fc receptor gamma-chain.
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Molecular Weight
- ~58kDa (SDS-PAGE)
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UniProt
- Q9JKF4
Target
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