QDPR Protein (AA 1-244) (His tag)

Catalog No. ABIN2746030

This Recombinant QDPR protein is produced in Human Cells.

Quick Overview for QDPR Protein (AA 1-244) (His tag) (ABIN2746030)

Target: QDPR (Quinoid Dihydropteridine Reductase (QDPR))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 1-244

Purification tag / Conjugate: This QDPR protein is labelled with His tag.

Purpose: Recombinant Human Dihydropteridine Reductase/QDPR (C-6His)

Sequence: AAAAAAGEAR RVLVYGGRGA LGSRCVQAFR ARNWWVASVD VVENEEASAS IIVKMTDSFT EQADQVTAEV GKLLGEEKVD AILCVAGGWA GGNAKSKSLF KNCDLMWKQS IWTSTISSHL ATKHLKEGGL LTLAGAKAAL DGTPGMIGYG MAKGAVHQLC QSLAGKNSGM PPGAAAIAVL PVTLDTPMNR KSMPEADFSS WTPLEFLVET FHDWITGKNR PSSGSLIQVV TTEGRTELTP AYFVDHHHHH H

Characteristics: Recombinant Human Dihydropteridine Reductase/QDPR is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-Phe244) of Human QDPR fused with a polyhistidine tag at the C-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, pH 8.0.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: QDPR (Quinoid Dihydropteridine Reductase (QDPR))

Alternative Name: QDPR

Sub Type: Fusionprotein

Background: Dihydropteridine reductase, also known as HDHPR and Quinoid dihydropteridine reductase, QDPR and DHPR, belongs to the short-chain dehydrogenases/reductases (SDR) family. QDPR exists as a homodimer. QDPR is part of the pathway that recycles a substance called tetrahydrobiopterin, also known as BH4 and tryptophan hydroxylases. The regeneration of this substance is critical for the proper processing of several other amino acids in the body. Tetrahydrobiopterin also helps produce certain chemicals in the brain called neurotransmitters, which transmit signals between nerve cells. Defects in QDPR are the cause of BH4-deficient hyperphenylalaninemia type C (HPABH4C) which is a rare autosomal recessive disorder and is lethal.
Alternative Names: Dihydropteridine Reductase, HDHPR, Quinoid Dihydropteridine Reductase, QDPR, DHPR

Molecular Weight: 26.8 kDa

UniProt: P09417