QDPR Protein (His tag)
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- Target See all QDPR Proteins
- QDPR (Quinoid Dihydropteridine Reductase (QDPR))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This QDPR protein is labelled with His tag.
- Purpose
- Recombinant Human Dihydropteridine Reductase/QDPR Protein (His Tag)
- Sequence
- Ala2-Phe244
- Characteristics
- Recombinant Human Dihydropteridine Reductase is produced by our Mammalian expression system and the target gene encoding Ala2-Phe244 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product QDPR Protein
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Quinoid Dihydropteridine Reductase (QDPR) (AA 1-244) protein (GST tag)
QDPR Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Quinoid Dihydropteridine Reductase (QDPR) (AA 1-241) protein (Strep Tag)Crystallography grade QDPR Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Quinoid Dihydropteridine Reductase (QDPR) (AA 2-244) protein (His tag)Crystallography grade QDPR Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Quinoid Dihydropteridine Reductase (QDPR) protein (Myc-DYKDDDDK Tag)QDPR Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, pH 8.0.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- QDPR (Quinoid Dihydropteridine Reductase (QDPR))
- Alternative Name
- Dihydropteridine Reductase/QDPR (QDPR Products)
- Synonyms
- DHPR Protein, PKU2 Protein, SDR33C1 Protein, 2610008L04Rik Protein, D5Ertd371e Protein, Dhpr Protein, QDPR Protein, qdpr Protein, MGC131372 Protein, DDBDRAFT_0168923 Protein, DDBDRAFT_0237752 Protein, DDB_0168923 Protein, DDB_0237752 Protein, CG4665 Protein, Dmel\\CG4665 Protein, si:ch211-89f22.2 Protein, quinoid dihydropteridine reductase Protein, quinoid dihydropteridine reductase S homeolog Protein, dihydropteridine reductase Protein, Dihydropteridine reductase Protein, bifunctional oxygen-insensitive NAD(P)H nitroreductase/dihydropteridine reductase NfnB Protein, quinoid dihydropteridine reductase a Protein, QDPR Protein, Qdpr Protein, qdpr Protein, qdpr.S Protein, Dhpr Protein, nfnB Protein, LOC5568428 Protein, dhpr Protein, qdpra Protein
- Background
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Background: Dihydropteridine reductase, also known as HDHPR and Quinoid dihydropteridine reductase, QDPR and DHPR, belongs to the short-chain dehydrogenases/reductases (SDR) family. QDPR exists as a homodimer. QDPR is part of the pathway that recycles a substance called tetrahydrobiopterin, also known as BH4 and tryptophan hydroxylases. The regeneration of this substance is critical for the proper processing of several other amino acids in the body. Tetrahydrobiopterin also helps produce certain chemicals in the brain called neurotransmitters, which transmit signals between nerve cells. Defects in QDPR are the cause of BH4-deficient hyperphenylalaninemia type C (HPABH4C) which is a rare autosomal recessive disorder and is lethal.
Synonym: Dihydropteridine Reductase, HDHPR, Quinoid Dihydropteridine Reductase, QDPR, DHPR
- Molecular Weight
- 26.8 kDa
- UniProt
- P09417
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