CXCL3 Protein
Quick Overview for CXCL3 Protein (ABIN2830013)
Target
See all CXCL3 ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Sequence
- ASVVTELRCQ CLQTLQGIHL KNIQSVNVRS PGPHCAQTEV IATLKNGKKA CLNPASPMVQ KIIEKILNKG STN
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Characteristics
- Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected human 293 cells is in a concentration range of 10-100 ng/mL.
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Sterility
- 0.2 μm filtered
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Chemokine (C-X-C Motif) Ligand 3 (CXCL3) protein (His tag)
CXCL3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Chemokine (C-X-C Motif) Ligand 3 (CXCL3) (AA 1-107) protein (GST tag)CXCL3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chemokine (C-X-C Motif) Ligand 3 (CXCL3) (AA 35-107), (full length) protein (His tag)CXCL3 Host: Escherichia coli (E. coli) Recombinant 90 % ELISA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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- CXCL3 (Chemokine (C-X-C Motif) Ligand 3 (CXCL3))
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Alternative Name
- CXCL3
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Background
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Relevance: Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes. {ECO:0000250, ECO:0000269|PubMed:10095777}.
Synonyms: GRO-gamma, Growth-regulated protein gamma, GRO-gamma, Macrophage inflammatory protein 2-beta, MIP2-beta -
Molecular Weight
- 7.9 kDa
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UniProt
- P19876
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Autophagy
Target
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