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CXCL6 Protein

This Recombinant CXCL6 protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN2830025

Quick Overview for CXCL6 Protein (ABIN2830025)

Target

See all CXCL6 Proteins
CXCL6 (Chemokine (C-X-C Motif) Ligand 6 (CXCL6))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 6
  • 1
  • 1
Human

Source

  • 3
  • 2
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Application

Functional Studies (Func)

Purity

>98 % as determined by SDS-PAGE and HPLC.
  • Sequence

    VLTELRCTCL RVTLRVNPKT IGKLQVFPAG PQCSKVEVVA SLKNGKQVCL DPEAPFLKKV IQKILDSGNK KN

    Characteristics

    Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human neutrophils is in a concentration range of 10-50 ng/mL.

    Sterility

    0.2 μm filtered
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    PBS, pH 7.4

    Storage

    -20 °C
  • Target

    CXCL6 (Chemokine (C-X-C Motif) Ligand 6 (CXCL6))

    Alternative Name

    CXCL6

    Background

    Relevance: Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7). {ECO:0000269|PubMed:18443119, ECO:0000269|PubMed:8399143, ECO:0000269|PubMed:8423327, ECO:0000269|PubMed:9057843}.
    Synonyms: Chemokine alpha 3, Granulocyte chemotactic protein 2, GCP-2, Small-inducible cytokine B6,

    Molecular Weight

    7.9 kDa

    UniProt

    P80162
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