CXCL6 Protein
Quick Overview for CXCL6 Protein (ABIN2830025)
Target
See all CXCL6 ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Sequence
- VLTELRCTCL RVTLRVNPKT IGKLQVFPAG PQCSKVEVVA SLKNGKQVCL DPEAPFLKKV IQKILDSGNK KN
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Characteristics
- Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human neutrophils is in a concentration range of 10-50 ng/mL.
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Sterility
- 0.2 μm filtered
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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- CXCL6 (Chemokine (C-X-C Motif) Ligand 6 (CXCL6))
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Alternative Name
- CXCL6
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Background
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Relevance: Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7). {ECO:0000269|PubMed:18443119, ECO:0000269|PubMed:8399143, ECO:0000269|PubMed:8423327, ECO:0000269|PubMed:9057843}.
Synonyms: Chemokine alpha 3, Granulocyte chemotactic protein 2, GCP-2, Small-inducible cytokine B6, -
Molecular Weight
- 7.9 kDa
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UniProt
- P80162
Target
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