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Nerve Growth Factor Protein (NGF) (AA 122-241)

This Recombinant Nerve Growth Factor protein is produced in Mammalian Cells.
Catalog No. ABIN2830300

Quick Overview for Nerve Growth Factor Protein (NGF) (AA 122-241) (ABIN2830300)

Target

See all Nerve Growth Factor (NGF) Proteins
Nerve Growth Factor (NGF)

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 8
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Human

Source

  • 26
  • 2
  • 2
  • 1
Mammalian Cells

Application

Functional Studies (Func)

Purity

>90 % as determined by SDS-PAGE.
  • Protein Characteristics

    AA 122-241

    Sequence

    Ser122-Ala241, Accession # CAA36832

    Characteristics

    Biological Activity: The ED50, as determined by a cell proliferation assay using human TF-1 cells, is less than 2 ng/mL.

    Sterility

    0.2 μm filtered
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    0.2 % acetic acid

    Storage

    -20 °C
  • Target

    Nerve Growth Factor (NGF)

    Alternative Name

    NGF

    Background

    Relevance: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177). {ECO:0000269|PubMed:20164177}.
    Synonyms: Beta-NGF,

    Molecular Weight

    13.5 kDa

    UniProt

    P01138

    Pathways

    Regulation of Cell Size
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