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IL-3 Protein

This Recombinant IL-3 protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN2830783

Quick Overview for IL-3 Protein (ABIN2830783)

Target

See all IL-3 Proteins
IL-3 (Interleukin 3 (IL-3))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 22
  • 15
  • 5
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Rhesus Monkey

Source

  • 29
  • 6
  • 6
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Application

Functional Studies (Func)

Purity

>98 % as determined by SDS-PAGE and HPLC.
  • Sequence

    APMTQTTSLK TSWAKCSNMI DEIITHLNQP PLPSPDFNNL NEEDQTILVE KNLRRSNLEA FSKAVKSLQN ASAIESILKN LPPCLPMATA APTRPPIRIT NGDRNDFRRK LKFYLKTLEN EQAQ

    Characteristics

    Biological Activity: Assay #1: Fully biologically active when compared to standard. The ED50 as determined by the dose- dependent stimulation of the proliferation of murine NFS-60 cells is less than 5.0 ng/mL, corresponding to a specific activity of > 2 x 105 IU/mg. Assay #2:

    Sterility

    0.2 μm filtered
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    PBS, pH 7.4, 5 % trehalose

    Storage

    -20 °C
  • Target

    IL-3 (Interleukin 3 (IL-3))

    Alternative Name

    IL3

    Background

    Relevance: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages., This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes.
    Synonyms: IL-3, Mast cell growth factor, MCGF, Multipotential colony-stimulating factor, P-cell-stimulating factor

    Molecular Weight

    14.0 kDa

    UniProt

    P25140

    Pathways

    JAK-STAT Signaling, Regulation of Carbohydrate Metabolic Process, Autophagy
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