IL-4 Protein

Catalog No. ABIN2830786

Recombinant IL-4 protein expressed in Escherichia coli (E. coli).

Quick Overview for IL-4 Protein (ABIN2830786)

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Protein Type: Recombinant

Biological Activity: Active

Origin: Rhesus Monkey

Source: Escherichia coli (E. coli)

Application: Functional Studies (Func)

Purity: >96 % as determined by SDS-PAGE and HPLC.

Product Details

Sequence: HNCHIALREI IETLNSLTEQ KTLCTKLTIT DILAASKNTT EKETFCRAAT VLRQFYSHHE KDTRCLGATA QQFHRHKQLI RFLKRLDRNL WGLAGLNSCP VKEANQSTLE DFLERLKTIM REKYSKCSS

Characteristics: Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 1.0 ng/mL, corresponding to a specific activity of ＞ 1.0 x 106 IU/mg.

Sterility: 0.2 μm filtered

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 2 x PBS, pH 7.4, 5 % trehalose

Storage: -20 °C

Target Details

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Alternative Name: IL4

Background: Relevance: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes (By similarity). {ECO:0000250}.
Synonyms: IL-4, BSF-1, Lymphocyte stimulatory factor 1

Molecular Weight: 14.9 kDa

UniProt: P51492

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation