CD163 Protein (CD163) (AA 42-1045) (His tag)
Quick Overview for CD163 Protein (CD163) (AA 42-1045) (His tag) (ABIN2870623)
Target
See all CD163 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 42-1045
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Purification tag / Conjugate
- This CD163 protein is labelled with His tag.
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Sequence
- AA 42-1045
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Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 110.4 kDa. The protein migrates as 135-140 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Handling Advice
- Please avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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- CD163
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Alternative Name
- CD163
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Background
- Scavenger receptor cysteine-rich type 1 protein M130 (CD163) is also known as hemoglobin scavenger receptor, which is a scavenger receptor for the hemoglobin-haptoglobin complex. CD163 has also been shown to mark cells of monocyte/macrophage lineage. A soluble form of the receptor exists in plasma, commonly denoted sCD163. sCD163 is generated by ectodomain shedding of the membrane bound receptor. sCD163 is upregulated in a large range of inflammatory diseases including liver cirrhosis, type 2 diabetes, macrophage activation syndrome, Gaucher's disease, sepsis, HIV infection, rheumatoid arthritis and Hodgkin Lymphoma.
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Molecular Weight
- 110.4 kDa
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UniProt
- Q86VB7
Target
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