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CD163 Protein (CD163) (AA 42-1045) (His tag)

Recombinant CD163 protein expressed in HEK-293 Cells.
Catalog No. ABIN2870623
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Quick Overview for CD163 Protein (CD163) (AA 42-1045) (His tag) (ABIN2870623)

Target

See all CD163 Proteins
CD163

Protein Type

Recombinant

Origin

  • 13
  • 8
  • 3
  • 2
Human

Source

  • 9
  • 6
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
HEK-293 Cells

Purity

>95 % as determined by SDS-PAGE.
  • Protein Characteristics

    AA 42-1045

    Purification tag / Conjugate

    This CD163 protein is labelled with His tag.

    Sequence

    AA 42-1045

    Characteristics

    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 110.4 kDa. The protein migrates as 135-140 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    Endotoxin Level

    Less than 1.0 EU per μg by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    PBS, pH 7.4

    Handling Advice

    Please avoid repeated freeze-thaw cycles.

    Storage

    -20 °C
  • Target

    CD163

    Alternative Name

    CD163

    Background

    Scavenger receptor cysteine-rich type 1 protein M130 (CD163) is also known as hemoglobin scavenger receptor, which is a scavenger receptor for the hemoglobin-haptoglobin complex. CD163 has also been shown to mark cells of monocyte/macrophage lineage. A soluble form of the receptor exists in plasma, commonly denoted sCD163. sCD163 is generated by ectodomain shedding of the membrane bound receptor. sCD163 is upregulated in a large range of inflammatory diseases including liver cirrhosis, type 2 diabetes, macrophage activation syndrome, Gaucher's disease, sepsis, HIV infection, rheumatoid arthritis and Hodgkin Lymphoma.

    Molecular Weight

    110.4 kDa

    UniProt

    Q86VB7
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