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CLEC4C Protein (AA 45-213) (His-SUMO Tag)

CLEC4C Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN4975581
  • Target See all CLEC4C products
    CLEC4C (C-Type Lectin Domain Family 4, Member C (CLEC4C))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 45-213
    Origin
    • 3
    • 3
    Human
    Source
    • 5
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This CLEC4C protein is labelled with His-SUMO Tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    NFMYSKTVKR LSKLREYQQY HPSLTCVMEG KDIEDWSCCP TPWTSFQSSC YFISTGMQSW TKSQKNCSVM GADLVVINTR EEQDFIIQNL KRNSSYFLGL SDPGGRRHWQ WVDQTPYNEN VTFWHSGEPN NLDERCAIIN FRSSEEWGWN DIHCHVPQKS ICKMKKIYI
    Purification
    SDS-PAGE
    Purity
    > 90 %
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Storage
    -80 °C,4 °C,-20 °C
    Storage Comment
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    CLEC4C (C-Type Lectin Domain Family 4, Member C (CLEC4C))
    Alternative Name
    CLC4C (CLEC4C Products)
    Synonyms
    BDCA2 Protein, CD303 Protein, CLECSF11 Protein, CLECSF7 Protein, DLEC Protein, HECL Protein, PRO34150 Protein, Clec4c Protein, C-type lectin domain family 4 member C Protein, CLEC4C Protein, LOC100733227 Protein
    Background
    Involved in antigen-capturing. Target ligand into antigen processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium. Does not se to bind mannose.
    Molecular Weight
    35.94 kDa
    UniProt
    Q8WTT0
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