ANGPTL4 Protein (DYKDDDDK-His Tag)

Catalog No. ABIN5505553

This Recombinant ANGPTL4 protein is expressed in HEK-293 Cells.

Quick Overview for ANGPTL4 Protein (DYKDDDDK-His Tag) (ABIN5505553)

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This ANGPTL4 protein is labelled with DYKDDDDK-His Tag.

Characteristics:

• Recombinant human Purified recombinant protein of human angiopoietin-like 4 (ANGPTL4), transcript variant 1, with C-terminal DDK/His tag, expressed in human cells, 20 μg (C-term DDK/His tag, transcript variant 1) protein expressed in Human HEK293 cells.
• Produced with end-sequenced ORF clone

Purification: Purified

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 1 x PBS, pH 7.4, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Alternative Name: angiopoietin-like 4

Background: This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4.

Molecular Weight: 18 kDa

NCBI Accession: NP_647475

Pathways: Regulation of Lipid Metabolism by PPARalpha