GFI1B Protein (His tag)

Catalog No. ABIN5505652

Product Details

Target: GFI1B (Growth Factor Independent 1B Transcription Repressor (GFI1B))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This GFI1B protein is labelled with His tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Purified recombinant protein of Human growth factor independent 1B transcription repressor (GFI1B), transcript variant 2, full length, with N-terminal HIS tag, expressed in E. coli, 50 μg (full length, N-term HIS tag, transcript variant 2) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Purification: Purified

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: GFI1B (Growth Factor Independent 1B Transcription Repressor (GFI1B))

Alternative Name: growth factor independent 1B transcription repressor (GFI1B Products)

Synonyms: GFI1B Protein, GFI Protein, znf544 Protein, MGC80648 Protein, Gfi-1B Protein, growth factor independent 1B transcriptional repressor Protein, growth factor independent 1B transcription repressor L homeolog Protein, Zinc finger protein Gfi-1b Protein, growth factor independent 1B Protein, GFI1B Protein, Gfi1b Protein, gfi1b.L Protein, gfi1b Protein

Background: This gene encodes a zinc-finger containing transcriptional regulator that is primarily expressed in cells of hematopoietic lineage. The encoded protein complexes with numerous other transcriptional regulatory proteins including GATA-1, runt-related transcription factor 1 and histone deacetylases to control expression of genes involved in the development and maturation of erythrocytes and megakaryocytes. Mutations in this gene are the cause of the autosomal dominant platelet disorder, platelet-type bleeding disorder-17. Alternate splicing results in multiple transcript variants.

Molecular Weight: 32.2 kDa

NCBI Accession: NP_001128503

Pathways: Cellular Response to Molecule of Bacterial Origin