KDM5A Protein (DYKDDDDK Tag)

Catalog No. ABIN5505708

This Recombinant KDM5A protein is produced in HEK-293 Cells.

Quick Overview for KDM5A Protein (DYKDDDDK Tag) (ABIN5505708)

Target: KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This KDM5A protein is labelled with DYKDDDDK Tag.

Characteristics:

• Recombinant human KDM5A / JARID1A (full length, C-term DDK tag) protein expressed in Human HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 50 mM Tris-HCl, pH 8.0, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))

Alternative Name: KDM5A / JARID1A

Background: This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression.

Molecular Weight: 192 kDa

NCBI Accession: NP_001036068

Pathways: Chromatin Binding, Warburg Effect