CD28H (partial) protein (Fc Tag)

Catalog No. ABIN5608281

This Recombinant protein is produced in HEK-293 Cells.

Quick Overview for CD28H (partial) protein (Fc Tag) (ABIN5608281)

Target: CD28H

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Western Blotting (WB)

Purity: >95 % as determined by SDS-PAGE.

Product Details

Protein Characteristics: partial

Purification tag / Conjugate: Fc Tag

Sequence: Leu 23 - Gly 150

Endotoxin Level: Endotoxin level is less than 1.0 EU per ug by the LAL method.

Application Details

Application Notes: This recombinant protein can be used for WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 50 mM Tris, 100 mM Glycine, pH 7.5

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C,-80 °C

Storage Comment: Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.

Target Details

Target: CD28H

Background: CD28 homolog (CD28H), also called transmembrane and immunoglobulin domain containing 2 (TMIGD2) and IGPR-1,is encoded by the TMIGD2 gene. CD28H is constitutively expressed on naive T and NK cells. After interaction of CD28 homolog with B7 homologue,the peripheral effector and memory T cells can be activated and proliferated by Akt-dependent signalling cascade. Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.

Molecular Weight: 40.6 kDa

Gene ID: 126259