PSME3 Protein (PSME3) (partial) (His tag)
Quick Overview for PSME3 Protein (PSME3) (partial) (His tag) (ABIN5608460)
Target
See all PSME3 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- partial
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Purification tag / Conjugate
- This PSME3 protein is labelled with His tag.
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Sequence
- Met 1 - Tyr 254
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Endotoxin Level
- Endotoxin level is less than 1.0 EU per ug by the LAL method.
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PSME3 (PSME3) (AA 1-267) protein (His tag)
PSME3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
PSME3 (PSME3) (AA 2-254) protein (His tag)PSME3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
PSME3 (PSME3) (AA 1-254) protein (GST tag)PSME3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
PSME3 (PSME3) (AA 1-254) protein (His tag)PSME3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90% by SDS-PAGE SDS
PSME3 (PSME3) (AA 2-252), (partial) protein (GST tag)PSME3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
PSME3 (PSME3) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)PSME3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
- This recombinant protein can be used for WB.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 50 mM Tris, 200 mM NaCl, pH 8.0
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
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- PSME3
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Alternative Name
- PSME3
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Background
- Proteasome activator complex subunit 3 (PSME3),a member of the PA28 family, is also known as 11S regulator complex subunit gamma (REG-gamma), activator of multicatalytic protease subunit 3 and proteasome activator 28 subunit gamma (PA28gamma). PSME3 activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. PSME3 can also facilitate the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. Furthermore,PSME3 may also be involved in cell cycle regulation.
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Molecular Weight
- 30.3 kDa
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Gene ID
- 10197
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NCBI Accession
- NP_00578
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UniProt
- P61289
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Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Hepatitis C, Synthesis of DNA
Target
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