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Hemopexin Protein (HPX)

Native Hemopexin protein expressed in Human and has been mentioned in 8+ publications.
Catalog No. ABIN5662823

Quick Overview for Hemopexin Protein (HPX) (ABIN5662823)

Target

See all Hemopexin (HPX) Proteins
Hemopexin (HPX)

Protein Type

Native

Origin

  • 11
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Source

  • 10
  • 6
  • 6
  • 1
  • 1
Human

Purity

>95 %
  • Cross-Reactivity (Details)

    Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
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  • Application Notes

    For use in: SDS

    Comment

    Extinction Coefficient: 1.97

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    11.9 mM phosphate, 137 mM NaCl, 2.7 mM KCl, pH 7.4.

    Storage

    -20 °C

    Storage Comment

    -20°C
  • Kozlik, Sanda, Goldman: "Nano reversed phase versus nano hydrophilic interaction liquid chromatography on a chip in the analysis of hemopexin glycopeptides." in: Journal of chromatography. A, Vol. 1519, pp. 152-155, (2017) (PubMed).

    Kozlik, Goldman, Sanda: "Study of structure-dependent chromatographic behavior of glycopeptides using reversed phase nanoLC." in: Electrophoresis, Vol. 38, Issue 17, pp. 2193-2199, (2017) (PubMed).

    Sakamoto, Kim, Hara, Kamada, Caballero-Flores, Tolosano, Soares, Puente, Inohara, Núñez: "IL-22 Controls Iron-Dependent Nutritional Immunity Against Systemic Bacterial Infections." in: Science immunology, Vol. 2, Issue 8, (2017) (PubMed).

    Aggarwal, Lam, Bolisetty, Carlisle, Traylor, Agarwal, Matalon: "Heme Attenuation Ameliorates Irritant Gas Inhalation-Induced Acute Lung Injury." in: Antioxidants & redox signaling, Vol. 24, Issue 2, pp. 99-112, (2016) (PubMed).

    Mehta, Grijalva, Hama, Wagner, Navab, Fogelman, Reddy: "Apolipoprotein E-/- Mice Lacking Hemopexin Develop Increased Atherosclerosis via Mechanisms That Include Oxidative Stress and Altered Macrophage Function." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 36, Issue 6, pp. 1152-63, (2016) (PubMed).

    Kassa, Jana, Meng, Alayash: "Differential heme release from various hemoglobin redox states and the upregulation of cellular heme oxygenase-1." in: FEBS open bio, Vol. 6, Issue 9, pp. 876-84, (2016) (PubMed).

    Lin, Liu, Huang, Van Engelen, Thundivalappil, Riley, Super, Watters, Smith, Brinkman, Ingber, Warren: "Purified and recombinant hemopexin: protease activity and effect on neutrophil chemotaxis." in: Molecular medicine (Cambridge, Mass.), (2016) (PubMed).

    Kassa, Jana, Strader, Meng, Jia, Wilson, Alayash: "Sickle Cell Hemoglobin in the Ferryl State Promotes βCys-93 Oxidation and Mitochondrial Dysfunction in Epithelial Lung Cells (E10)." in: The Journal of biological chemistry, Vol. 290, Issue 46, pp. 27939-58, (2015) (PubMed).

  • Target

    Hemopexin (HPX)

    Alternative Name

    Hemopexin

    Background

    HPX, HX, Hpxn, beta-1B-glycoprotein, transporter

    Molecular Weight

    57 kDa

    Pathways

    Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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