CD47 Protein (CD47) (AA 19-141) (His tag)
Quick Overview for CD47 Protein (CD47) (AA 19-141) (His tag) (ABIN5674615)
Target
See all CD47 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 19-141
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Purification tag / Conjugate
- This CD47 protein is labelled with His tag.
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Sequence
- AA 19-141
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Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 15.8 kDa. The protein migrates as 30-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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CD47 (CD47) (AA 19-141) (Active) protein (His tag)
CD47 Origin: Rhesus Monkey, Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD47 (CD47) (AA 19-141) protein (His tag,mFc Tag)CD47 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. IA, ADA, ScA, AM
CD47 (CD47) (AA 19-139) (Active) protein (Biotin,His-Avi Tag)CD47 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD47 (CD47) (AA 19-140) (Active) protein (His tag)CD47 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD47 (CD47) (AA 19-139) (Active) protein (Fc Tag)CD47 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD47 (CD47) (AA 19-139) (Active) protein (His tag)CD47 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD47 (CD47) (AA 19-139) (Active) protein (Fc Tag,AVI tag,Biotin)CD47 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD47 (CD47) protein (DYKDDDDK Tag)CD47 Origin: Human Host: HEK-293 Cells Synthetic Nanodisc ELISA, Imm, cryo-EM, SPR, PhD
CD47 (CD47) (AA 19-139) (Active) protein (His tag,AVI tag)CD47 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
CD47 (CD47) (AA 19-139) (Active) protein (His tag,AVI tag,Biotin)CD47 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Handling Advice
- Please avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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- CD47
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Alternative Name
- CD47
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Background
- Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.
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Molecular Weight
- 15.8 kDa
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NCBI Accession
- NP_001253446
Target
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