ACVA Protein

Catalog No. ABIN5676019

This Recombinant ACVA protein is expressed in Hi-5 Cells.

Quick Overview for ACVA Protein (ABIN5676019)

Target: ACVA (Activin A (ACVA))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Hi-5 Cells

Purity: > 95 % pure

Product Details

Sequence: GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC EGECPSHIAG TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS MLYYDDGQNI IKKDIQNMIV EECGCS

Characteristics: Purified recombinant Human Activin A protein
Expression System: Hi-5 cells
Bioactivity: The ED50 as determined by its ability to inhibit the proliferation of Mouse MPC-11 cells is ? 2 ng/mL, corresponding to a specific activity of ? 5 x 10^5 units/mg.

Endotoxin Level: < 0.1 ng per µg (1 EU/µg).

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Comment:

Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in water to a concentration of 0.5 mg/mL. Do not vortex.

Buffer: Lyophilized from 10 mM Citric Acid pH 3.0.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Target Details

Target: ACVA (Activin A (ACVA))

Alternative Name: Activin A

Background: Activin A is a TGF beta family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in post-menopausal woman have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF beta antagonist, Follistatin.
Alternative Names: Activin beta-A protein, Inhibin beta-A protein

Molecular Weight: 26 kDa

Pathways: Hormone Transport, Peptide Hormone Metabolism