CSNK1A1 Protein (AA 2-337) (His tag)

Catalog No. ABIN5709341

This Recombinant CSNK1A1 protein is expressed in Escherichia coli (E. coli).

Quick Overview for CSNK1A1 Protein (AA 2-337) (His tag) (ABIN5709341)

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 90 %

Product Details

Protein Characteristics: AA 2-337

Purification tag / Conjugate: This CSNK1A1 protein is labelled with His tag.

Sequence: ASSSGSKAEF IVGGKYKLVR KIGSGSFGDI YLAINITNGE EVAVKLESQK ARHPQLLYES KLYKILQGGV GIPHIRWYGQ EKDYNVLVMD LLGPSLEDLF NFCSRRFTMK TVLMLADQMI SRIEYVHTKN FIHRDIKPDN FLMGIGRHCN KLFLIDFGLA KKYRDNRTRQ HIPYREDKNL TGTARYASIN AHLGIEQSRR DDMESLGYVL MYFNRTSLPW QGLKAATKKQ KYEKISEKKM STPVEVLCKG FPAEFAMYLN YCRGLRFEEA PDYMYLRQLF RILFRTLNHQ YDYTFDWTML KQKAAQQAAS SSGQGQQAQT PTGKQTDKTK SNMKGF

Purification: SDS-PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Alternative Name: KC1A

Background: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis.

Molecular Weight: 42.9 kDa

UniProt: P48729

Pathways: WNT Signaling, Hedgehog Signaling