EPHX2 Protein (AA 1-555, full length) (His-SUMO Tag)

Catalog No. ABIN5709475

Product Details

Target: EPHX2 (Epoxide Hydrolase 2, Cytoplasmic (EPHX2))

Protein Type: Recombinant

Protein Characteristics: full length, AA 1-555

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This EPHX2 protein is labelled with His-SUMO Tag.

Application: SDS-PAGE (SDS)

Sequence: MTLRAAVFDL DGVLALPAVF GVLGRTEEAL ALPRGLLNDA FQKGGPEGAT TRLMKGEITL SQWIPLMEEN CRKCSETAKV CLPKNFSIKE IFDKAISARK INRPMLQAAL MLRKKGFTTA ILTNTWLDDR AERDGLAQLM CELKMHFDFL IESCQVGMVK PEPQIYKFLL DTLKASPSEV VFLDDIGANL KPARDLGMVT ILVQDTDTAL KELEKVTGIQ LLNTPAPLPT SCNPSDMSHG YVTVKPRVRL HFVELGSGPA VCLCHGFPES WYSWRYQIPA LAQAGYRVLA MDMKGYGESS APPEIEEYCM EVLCKEMVTF LDKLGLSQAV FIGHDWGGML VWYMALFYPE RVRAVASLNT PFIPANPNMS PLESIKANPV FDYQLYFQEP GVAEAELEQN LSRTFKSLFR ASDESVLSMH KVCEAGGLFV NSPEEPSLSR MVTEEEIQFY VQQFKKSGFR GPLNWYRNME RNWKWACKSL GRKILIPALM VTAEKDFVLV PQMSQHMEDW IPHLKRGHIE DCGHWTQMDK PTEVNQILIK WLDSDARNPP VVSKM

Purification: SDS-PAGE

Purity: > 90 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: EPHX2 (Epoxide Hydrolase 2, Cytoplasmic (EPHX2))

Alternative Name: HYES (EPHX2 Products)

Synonyms: CEH Protein, SEH Protein, Eph2 Protein, sEP Protein, epoxide hydrolase 2 Protein, soluble epoxide hydrolase Protein, Soluble epoxide hydrolase Protein, alpha/beta hydrolase Protein, epoxide hydrolase 2, cytoplasmic Protein, EPHX2 Protein, SEH2 Protein, PTRG_01276 Protein, Deima_0402 Protein, Deipr_0144 Protein, Psed_0418 Protein, Fluta_3767 Protein, HALXA_RS12710 Protein, Ephx2 Protein

Background: Bifunctional enzyme. The C-terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides, oxiranes) and arene oxides. Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides. Also determines steady-state levels of physiological mediators. The N-terminal domain has lipid phosphatase activity, with the highest activity towards threo-9,10-phosphonooxy-hydroxy-octadecanoic acid, followed by erythro-9,10-phosphonooxy-hydroxy-octadecanoic acid, 12-phosphonooxy-octadec-9Z-enoic acid, 12-phosphonooxy-octadec-9E-enoic acid, and p-nitrophenyl phospate.

Molecular Weight: 78.57 kDa

UniProt: P34913