Major Royal Jelly Protein 1 (MRJP1) (AA 20-432) protein (GST tag)

Catalog No. ABIN5711193

Recombinant Major Royal Jelly Protein 1 protein expressed in Escherichia coli (E. coli).

Quick Overview for Major Royal Jelly Protein 1 (MRJP1) (AA 20-432) protein (GST tag) (ABIN5711193)

Target: Major Royal Jelly Protein 1 (MRJP1)

Protein Type: Recombinant

Origin: Apis mellifera

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 90 %

Product Details

Protein Characteristics: AA 20-432

Purification tag / Conjugate: GST tag

Sequence: NILRGESLNK SLPILHEWKF FDYDFGSDER RQDAILSGEY DYKNNYPSDI DQWHDKIFVT MLRYNGVPSS LNVISKKVGD GGPLLQPYPD WSFAKYDDCS GIVSASKLAI DKCDRLWVLD SGLVNNTQPM CSPKLLTFDL TTSQLLKQVE IPHDVAVNAT TGKGRLSSLA VQSLDCNTNS DTMVYIADEK GEGLIVYHNS DDSFHRLTSN TFDYDPKFTK MTIDGESYTA QDGISGMALS PMTNNLYYSP VASTSLYYVN TEQFRTSDYQ QNDIHYEGVQ NILDTQSSAK VVSKSGVLFF GLVGDSALGC WNEHRTLERH NIRTVAQSDE TLQMIASMKI KEALPHVPIF DRYINREYIL VLSNKMQKMV NNDFNFDDVN FRIMNANVNE LILNTRCENP DNDRTPFKIS IHL

Purification: SDS-PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: Major Royal Jelly Protein 1 (MRJP1)

Alternative Name: MRJP1

Background: Major royal jelly protein 1: induces the differentiation of honeybee larvae into queens through an Egfr-mediated signaling pathway. Promotes body size increase by activating p70 S6 kinase, stimulates ovary development by augmenting the titer of vitellogenin (Vg) and juvenile hormone, and reduces developmental time by increasing the activity of mitogen-activated protein kinase and inducing the 20-hydroxyecdysone protein (20E). Most abundant protein found in the royal jelly which is the food of the queen honey bee larva. The royal jelly determines the development of the young larvae and is responsible for the high reproductive ability of the honeybee queen.Jellein-1: has antibacterial activity against the Gram-positive bacteria S.aureus ATCC 6535, S.saprophyticus and B.subtilis CCT2471, and the Gram-negative bacteria E.coli CCT1371, E.cloacae ATCC 23355, K.pneumoniae ATCC 13883 and P.aeruginosa ATCC 27853, and antifungal activity against C.albicans. Lack cytolytic activity and does not induce rat peritoneal mast cell degranulation.Jellein-2: has antibacterial activity against the Gram-positive bacteria S.aureus ATCC 6535, S.saprophyticus and B.subtilis CCT2471, and the Gram-negative bacteria E.coli CCT1371, E.cloacae ATCC 23355, K.pneumoniae ATCC 13883 and P.aeruginosa ATCC 27853, and antifungal activity against C.albicans. Lack cytolytic activity and does not induce rat peritoneal mast cell degranulation.Jellein-4: lacks antibacterial and antifungal activity. Lacks cytolytic activity and does not induce rat peritoneal mast cell degranulation.

Molecular Weight: 74.2 kDa

UniProt: O18330