Plexin A4 Protein (PLXNA4) (AA 24-522, partial) (His tag)

Catalog No. ABIN5711767

This Recombinant Plexin A4 protein is produced in Escherichia coli (E. coli).

Quick Overview for Plexin A4 Protein (PLXNA4) (AA 24-522, partial) (His tag) (ABIN5711767)

Target: Plexin A4 (PLXNA4)

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 90 %

Product Details

Protein Characteristics: partial, AA 24-522

Purification tag / Conjugate: This Plexin A4 protein is labelled with His tag.

Sequence: LLTRQPAPLS QKQRSFVTFR GEPAEGFNHL VVDERTGHIY LGAVNRIYKL SSDLKVLVTH ETGPDEDNPK CYPPRIVQTC NEPLTTTNNV NKMLLIDYKE NRLIACGSLY QGICKLLRLE DLFKLGEPYH KKEHYLSGVN ESGSVFGVIV SYSNLDDKLF IATAVDGKPE YFPTISSRKL TKNSEADGMF AYVFHDEFVA SMIKIPSDTF TIIPDFDIYY VYGFSSGNFV YFLTLQPEMV SPPGSTTKEQ VYTSKLVRLC KEDTAFNSYV EVPIGCERSG VEYRLLQAAY LSKAGAVLGR TLGVHPDDDL LFTVFSKGQK RKMKSLDESA LCIFILKQIN DRIKERLQSC YRGEGTLDLA WLKVKDIPCS SALLTIDDNF CGLDMNAPLG VSDMVRGIPV FTEDRDRMTS VIAYVYKNHS LAFVGTKSGK LKKSFGTGPQ GGITQEWIGV AGDPPGANIA SQEQMLCVYL QCSSHKAISD QRVQPLLCCF LNVPGNS

Purification: SDS-PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: Plexin A4 (PLXNA4)

Alternative Name: PLXA4

Background: Coreceptor for SA3A. Necessary for signaling by class 3 saphorins and subsequent rodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous syst. Class 3 saphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific saphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm .

Molecular Weight: 59.4 kDa

UniProt: Q9HCM2

Pathways: Regulation of Cell Size