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MBNL1 Protein (AA 1-382) (His-SUMO Tag)

This Recombinant MBNL1 protein is expressed in Escherichia coli (E. coli).

SDS

1 image

Catalog No. ABIN5711928

$488.40

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Quick Overview for MBNL1 Protein (AA 1-382) (His-SUMO Tag) (ABIN5711928)

Target

See all MBNL1 Proteins

MBNL1 (Muscleblind-like Protein 1 (MBNL1))

Protein Type

Recombinant

Origin

Human

Source

Escherichia coli (E. coli)

Application

SDS-PAGE (SDS)

Purity

> 90 %

Discover our top product MBNL1 Protein

Protein Characteristics

AA 1-382

Purification tag / Conjugate

This MBNL1 protein is labelled with His-SUMO Tag.

Sequence

MAVSVTPIRD TKWLTLEVCR EFQRGTCSRP DTECKFAHPS KSCQVENGRV IACFDSLKGR CSRENCKYLH PPPHLKTQLE INGRNNLIQQ KNMAMLAQQM QLANAMMPGA PLQPVPMFSV APSLATNASA AAFNPYLGPV SPSLVPAEIL PTAPMLVTGN PGVPVPAAAA AAAQKLMRTD RLEVCREYQR GNCNRGENDC RFAHPADSTM IDTNDNTVTV CMDYIKGRCS REKCKYFHPP AHLQAKIKAA QYQVNQAAAA QAAATAAAMG IPQAVLPPLP KRPALEKTNG ATAVFNTGIF QYQQALANMQ LQQHTAFLPP GSILCMTPAT SVVPMVHGAT PATVSAATTS ATSVPFAATA TANQIPIISA EHLTSHKYVT QM

Purification

SDS-PAGE
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Product

Expression System

Conjugate

Origin

Price starts at

MBNL1 Protein (AA 1-388) (His tag)

Expression System HEK-293 Cells

Conjugate His tag

Origin Human

Price starts at $12,595.45

MBNL1 Protein (AA 1-388) (Strep Tag)

Expression System Cell-free protein synthesis (CFPS)

Conjugate Strep Tag

Origin Human

Price starts at $20,480.57

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Muscleblind-like Protein 1 (MBNL1) (AA 1-341) protein (His tag)
custom-made MBNL1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Muscleblind-like Protein 1 (MBNL1) (AA 1-388) protein (His tag)
custom-made MBNL1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Muscleblind-like Protein 1 (MBNL1) (Transcript Variant 6) (Active) protein (Myc-DYKDDDDK Tag)
MBNL1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD, Func, PI Active

Muscleblind-like Protein 1 (MBNL1) (AA 1-343) protein (GST tag)
MBNL1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

Muscleblind-like Protein 1 (MBNL1) (AA 1-382) protein (GST tag)
MBNL1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

Muscleblind-like Protein 1 (MBNL1) (AA 1-341) protein (Strep Tag)
custom-made MBNL1 Origin: Mouse Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

Muscleblind-like Protein 1 (MBNL1) (AA 1-388) protein (Strep Tag)
custom-made MBNL1 Origin: Human Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

Muscleblind-like Protein 1 (MBNL1) (Transcript Variant 7) protein (Myc-DYKDDDDK Tag)
MBNL1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

Muscleblind-like Protein 1 (MBNL1) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)
MBNL1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

Muscleblind-like Protein 1 (MBNL1) (Transcript Variant 5) protein (Myc-DYKDDDDK Tag)
MBNL1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Liquid

Concentration

0.1-2 mg/mL

Buffer

20 mM Tris-HCl based buffer, pH 8.0

Storage

-80 °C,4 °C,-20 °C

Storage Comment

Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Target

MBNL1 (Muscleblind-like Protein 1 (MBNL1))

Alternative Name

MBNL1

Background

Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. Regulates the TNNT2 exon 5 skipping through competition with U2AF2. Inhibits the formation of the spliceosome A complex on intron 4 of TNNT2 pre-mRNA. Binds to the st-loop structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assbly. Binds to the 5'-YGCU(U/G)Y-3'consensus sequence. Binds to the IR RNA. Binds to expanded CUG repeat RNA, which folds into a hairpin structure containing GC base pairs and bulged, unpaired U residues.

Molecular Weight

57 kDa

UniProt

Q9NR56

Pathways

Ribonucleoprotein Complex Subunit Organization