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IFITM1 Protein (AA 1-36, Extracellular) (GST tag)

This Recombinant IFITM1 protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN5712123

Quick Overview for IFITM1 Protein (AA 1-36, Extracellular) (GST tag) (ABIN5712123)

Target

See all IFITM1 Proteins
IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))

Protein Type

Recombinant

Origin

  • 6
  • 2
Human

Source

  • 3
  • 2
  • 2
  • 1
Escherichia coli (E. coli)

Application

SDS-PAGE (SDS)

Purity

> 90 %
  • Protein Characteristics

    Extracellular, AA 1-36

    Purification tag / Conjugate

    This IFITM1 protein is labelled with GST tag.

    Sequence

    MHKEEHEVAV LGAPPSTILP RSTVINIHSE TSVPDH

    Purification

    SDS-PAGE
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  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.1-2 mg/mL

    Buffer

    20 mM Tris-HCl based buffer, pH 8.0

    Storage

    -80 °C,4 °C,-20 °C

    Storage Comment

    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target

    IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))

    Alternative Name

    IFM1

    Background

    IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). Can inhibit: influenza virus hagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation

    Molecular Weight

    31.3 kDa

    UniProt

    P13164
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