Angiopoietin 2 Protein (ANGPT2) (AA 19-485, partial) (His tag)
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- Target See all Angiopoietin 2 (ANGPT2) Proteins
- Angiopoietin 2 (ANGPT2)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-485, partial
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Angiopoietin 2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- YNNFRKSMDS IGKKQYQVQH GSCSYTFLLP EMDNCRSSSS PYVSNAVQRD APLEYDDSVQ RLQVLENIME NNTQWLMKLE NYIQDNMKKE MVEIQQNAVQ NQTAVMIEIG TNLLNQTAEQ TRKLTDVEAQ VLNQTTRLEL QLLEHSLSTN KLEKQILDQT SEINKLQDKN SFLEKKVLAM EDKHIIQLQS IKEEKDQLQV LVSKQNSIIE ELEKKIVTAT VNNSVLQKQQ HDLMETVNNL LTMMSTSNSA KDPTVAKEEQ ISFRDCAEVF KSGHTTNGIY TLTFPNSTEE IKAYCDMEAG GGGWTIIQRR EDGSVDFQRT WKEYKVGFGN PSGEYWLGNE FVSQLTNQQR YVLKIHLKDW EGNEAYSLYE HFYLSSEELN YRIHLKGLTG TAGKISSISQ PGNDFSTKDG DNDKCICKCS QMLTGGWWFD ACGPSNLNGM YYPQRQNTNK FNGIKWYYWK GSGYSLK
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product ANGPT2 Protein
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Angiopoietin 2 (ANGPT2) (AA 275-496) protein (His-Avi Tag)
ANGPT2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Angiopoietin 2 (ANGPT2) (AA 275-496) protein (His tag)ANGPT2 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Angiopoietin 2 (ANGPT2) (AA 275-496) protein (His-Avi Tag,Biotin)ANGPT2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Angiopoietin 2 (ANGPT2) (AA 275-496) protein (His tag)ANGPT2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Angiopoietin 2 (ANGPT2) (AA 19-496) protein (His tag)ANGPT2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Angiopoietin 2 (ANGPT2) protein (Fc Tag)ANGPT2 Origin: Mouse Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Angiopoietin 2 (ANGPT2) (AA 19-496) (Active) protein (His tag)ANGPT2 Origin: Mouse Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Angiopoietin 2 (ANGPT2) (AA 275-496) (Active) protein (His tag,AVI tag,Biotin)ANGPT2 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- Angiopoietin 2 (ANGPT2)
- Alternative Name
- ANGP2 (ANGPT2 Products)
- Background
- Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
- Molecular Weight
- 57.7 kDa
- UniProt
- O15123
- Pathways
- RTK Signaling
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