MCAM Protein (AA 50-646, partial) (His tag)
Quick Overview for MCAM Protein (AA 50-646, partial) (His tag) (ABIN5712730)
Target
See all MCAM ProteinsProtein Type
Origin
Source
Application
Purity
-
-
Protein Characteristics
- partial, AA 50-646
-
Purification tag / Conjugate
- This MCAM protein is labelled with His tag.
-
Sequence
- LSQSQGNLSH VDWFSVHKEK RTLIFRVRQG QGQSEPGEYE QRLSLQDRGA TLALTQVTPQ DERIFLCQGK RPRSQEYRIQ LRVYKAPEEP NIQVNPLGIP VNSKEPEEVA TCVGRNGYPI PQVIWYKNGR PLKEEKNRVH IQSSQTVESS GLYTLQSILK AQLVKEDKDA QFYCELNYRL PSGNHMKESR EVTVPVFYPT EKVWLEVEPV GMLKEGDRVE IRCLADGNPP PHFSISKQNP STREAEEETT NDNGVLVLEP ARKEHSGRYE CQGLDLDTMI SLLSEPQELL VNYVSDVRVS PAAPERQEGS SLTLTCEAES SQDLEFQWLR EETGQVLERG PVLQLHDLKR EAGGGYRCVA SVPSIPGLNR TQLVNVAIFG PPWMAFKERK VWVKENMVLN LSCEASGHPR PTISWNVNGT ASEQDQDPQR VLSTLNVLVT PELLETGVEC TASNDLGKNT SILFLELVNL TTLTPDSNTT TGLSTSTASP HTRANSTSTE RKLPEPESRG VVIVAVIVCI LVLAVLGAVL YFLYKKGKLP CRRSGKQEIT LPPSRKSELV VEVKSDKLPE EMGLLQGSSG DKRAPGDQGE KYIDLRH
-
Purification
- SDS-PAGE
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!Your project requires further customization? Contact us and discover our custom protein solutions
-
Melanoma Cell Adhesion Molecule (MCAM) (AA 24-559) protein (His tag)
MCAM Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Melanoma Cell Adhesion Molecule (MCAM) (AA 24-563) protein (His tag)MCAM Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Melanoma Cell Adhesion Molecule (MCAM) (AA 1-646) protein (GST tag)MCAM Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Melanoma Cell Adhesion Molecule (MCAM) (AA 24-646) protein (His-DYKDDDDK-Strep II Tag)MCAM Origin: Human Host: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Melanoma Cell Adhesion Molecule (MCAM) (AA 24-559) protein (His tag)MCAM Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 95% by SDS-PAGE SDS
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.1-2 mg/mL
-
Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
-
Storage
- -80 °C,4 °C,-20 °C
-
Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
-
-
- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
-
Alternative Name
- MUC18
-
Background
- Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elents of the vascular syst, thereby enhancing hatogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during bryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
-
Molecular Weight
- 70.7 kDa
-
UniProt
- P43121
Target
-
