CBX7 Protein (AA 1-251, full length) (His tag)
Quick Overview for CBX7 Protein (AA 1-251, full length) (His tag) (ABIN5713322)
Target
See all CBX7 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 1-251, full length
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Purification tag / Conjugate
- This CBX7 protein is labelled with His tag.
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Sequence
- MELSAIGEQV FAVESIRKKR VRKGKVEYLV KWKGWPPKYS TWEPEEHILD PRLVMAYEEK EERDRASGYR KRGPKPKRLL LQRLYSMDLR SSHKAKGKEK LCFSLTCPLG SGSPEGVVKA GAPELVDKGP LVPTLPFPLR KPRKAHKYLR LSRKKFPPRG PNLESHSHRR ELFLQEPPAP DVLQAAGEWE PAAQPPEEEA DADLAEGPPP WTPALPSSEV TVTDITANSI TVTFREAQAA EGFFRDRSGK F
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Purification
- SDS-PAGE
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Chromobox Homolog 7 (CBX7) (AA 1-251) protein (His tag)
custom-made CBX7 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Chromobox Homolog 7 (CBX7) (AA 1-158) protein (His tag)custom-made CBX7 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Chromobox Homolog 7 (CBX7) (AA 2-90) protein (His-IF2DI Tag)CBX7 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
Chromobox Homolog 7 (CBX7) (AA 1-251) protein (GST tag)CBX7 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Chromobox Homolog 7 (CBX7) (AA 1-251), (full length) protein (His tag)CBX7 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1-2 mg/mL
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Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
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Storage
- -80 °C,4 °C,-20 °C
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Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- CBX7 (Chromobox Homolog 7 (CBX7))
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Alternative Name
- CBX7
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Background
- Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin rodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.
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Molecular Weight
- 30.3 kDa
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UniProt
- O95931
Target
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