HSD11B2 Protein (AA 1-405, full length) (His tag)
Quick Overview for HSD11B2 Protein (AA 1-405, full length) (His tag) (ABIN5713514)
Target
See all HSD11B2 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- full length, AA 1-405
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Purification tag / Conjugate
- This HSD11B2 protein is labelled with His tag.
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Sequence
- MERWPWPSGG AWLLVAARAL LQLLRSDLRL GRPLLAALAL LAALDWLCQR LLPPPAALAV LAAAGWIALS RLARPQRLPV ATRAVLITGC DSGFGKETAK KLDSMGFTVL ATVLELNSPG AIELRTCCSP RLRLLQMDLT KPGDISRVLE FTKAHTTSTG LWGLVNNAGH NEVVADAELS PVATFRSCME VNFFGALELT KGLLPLLRSS RGRIVTVGSP AGDMPYPCLG AYGTSKAAVA LLMDTFSCEL LPWGVKVSII QPGCFKTESV RNVGQWEKRK QLLLANLPQE LLQAYGKDYI EHLHGQFLHS LRLAMSDLTP VVDAITDALL AARPRRRYYP GQGLGLMYFI HYYLPEGLRR RFLQAFFISH CLPRALQPGQ PGTTPPQDAA QDPNLSPGPS PAVAR
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Purification
- SDS-PAGE
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Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 1-386) protein (His tag)
custom-made HSD11B2 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 1-405) protein (His tag)custom-made HSD11B2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 1-405) protein (GST tag)HSD11B2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) protein (Myc-DYKDDDDK Tag)HSD11B2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1-2 mg/mL
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Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
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Storage
- -80 °C,4 °C,-20 °C
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Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))
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Alternative Name
- DHI2
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Background
- Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
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Molecular Weight
- 46.1 kDa
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UniProt
- P80365
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Pathways
- Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones
Target
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