Mago Nashi Homolog 2 Protein (AA 1-148) (His tag)

Catalog No. ABIN5853006

Product Details

Target: Mago Nashi Homolog 2 (MAGOHB) (Mago-Nashi Homolog B (MAGOHB))

Protein Type: Recombinant

Protein Characteristics: AA 1-148

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This Mago Nashi Homolog 2 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAVASDF YLRYYVGHKG KFGHEFLEFE FRPDGKLRYA NNSNYKNDVM IRKEAYVHKS VMEELKRIID DSEITKEDDA LWPPPDRVGR QELEIVIGDE HISFTTSKIG SLIDVNQSKD PEGLRVFYYL VQDLKCLVFS LIGLHFKIKP I

Purity: > 90 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 1  mM DTT 30 % glycerol, 0.15M NaCl

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: Mago Nashi Homolog 2 (MAGOHB) (Mago-Nashi Homolog B (MAGOHB))

Alternative Name: MAGOHB (MAGOHB Products)

Synonyms: MGN2 Protein, mago Protein, magoh Protein, 2010012C16Rik Protein, Mago Protein, Magoh Protein, Magoh-rs1 Protein, mago homolog B, exon junction complex core component Protein, MAGOHB Protein, Magohb Protein

Background: MAGOHB is involved in mRNA splicing and in the nonsense-mediated decay (NMD) pathway. Also, it is interacts with RBM8A and is part of the exon junction complex (EJC) containing NCBP1, NCBP2, RNPS1, RBM8A, SRRM1, NXF1, uPF3B, uPF2 and ALYREF/THOC4. Recombinant human MAGOHB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molecular Weight: 19.7kDa (171aa), confirmed by MALDI-TOF

NCBI Accession: NP_060518

UniProt: Q96A72