HNRNPK Protein (AA 1-276) (His tag)
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- Target See all HNRNPK Proteins
- HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-276
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HNRNPK protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMETEQPE ETFPNTETNG EFGKRPAEDM EEEQAFKRSR NTDEMVELRI LLQSKNAGAV IGKGGKNIKA LRTDYNASVS VPDSSGPERI LSISADIETI GEILKKIIPT LEEGLQLPSP TATSQLPLES DAVECLNYQH YKGSDFDCEL RLLIHQSLAG GIIGVKGAKI KELRENTQTT IKLFQECCPH STDRVVLIGG KPDRVVECIK IILDLISESP IKGRAQPYDP NFYDETYDYG GFTMMFDDRR GRPVGFPMRG RGGFDRMPPG RGGRPMPPS
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product HNRNPK Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 20 % glycerol, 1 mM DTT.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
- Alternative Name
- HNRNPK (HNRNPK Products)
- Synonyms
- CSBP Protein, HNRPK Protein, TUNP Protein, Csbp Protein, Hnrpk Protein, hnrpk Protein, MGC75642 Protein, wu:fb37h02 Protein, wu:fi34c04 Protein, zgc:66162 Protein, KBBP Protein, NOVA Protein, heterogeneous nuclear ribonucleoprotein K Protein, heterogeneous nuclear ribonucleoprotein K S homeolog Protein, heterogeneous nuclear ribonucleoprotein k Protein, HNRNPK Protein, Hnrnpk Protein, hnrnpk.S Protein, hnrnpk Protein, LOC5565718 Protein, CpipJ_CPIJ000130 Protein, NGK_p0004 Protein
- Background
- HNRNPK belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. HNRNPK is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. Recombinant human HNRNPK protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 33 kDa (299aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_002131
- UniProt
- P61978
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