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Ectodysplasin A2 Receptor Protein (EDA2R) (AA 1-138) (His tag)

Recombinant Ectodysplasin A2 Receptor protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN5853331

Quick Overview for Ectodysplasin A2 Receptor Protein (EDA2R) (AA 1-138) (His tag) (ABIN5853331)

Target

See all Ectodysplasin A2 Receptor (EDA2R) Proteins
Ectodysplasin A2 Receptor (EDA2R)

Protein Type

Recombinant

Origin

  • 9
  • 5
  • 2
Human

Source

  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Application

SDS-PAGE (SDS)

Purity

> 90 % by SDS - PAGE
  • Protein Characteristics

    AA 1-138

    Purification tag / Conjugate

    This Ectodysplasin A2 Receptor protein is labelled with His tag.

    Sequence

    MGSSHHHHHH SSGLVPRGSH MGSMDCQENE YWDQWGRCVT CQRCGPGQEL SKDCGYGEGG DAYCTACPPR RYKSSWGHHR CQSCITCAVI NRVQKVNCTA TSNAVCGDCL PRFYRKTRIG GLQDQECIPC TKQTPTSEVQ CAFQLSLVEA DAPTVPPQEA T
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  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Comment

    Denatured

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Liquid. 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % glycerol 0.4M urea

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target

    Ectodysplasin A2 Receptor (EDA2R)

    Alternative Name

    EDA2R

    Background

    EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. EDA2R specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Alternatively spliced transcript variants have been found for this gene. Recombinant human EDA2R protein , fused to His-tag at N-terminus, was expressed in E.coli.

    Molecular Weight

    17.7 kDa (161aa)

    NCBI Accession

    NP_001229239

    UniProt

    Q9HAV5
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