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Ectodysplasin A2 Receptor Protein (EDA2R) (AA 1-138) (Fc Tag)

EDA2R Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7274510
  • Target See all Ectodysplasin A2 Receptor (EDA2R) Proteins
    Ectodysplasin A2 Receptor (EDA2R)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-138
    Origin
    • 10
    • 5
    • 2
    Mouse
    Source
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Ectodysplasin A2 Receptor protein is labelled with Fc Tag.
    Purpose
    Mouse EDA2R Protein
    Sequence
    Met1-Thr138
    Characteristics
    Recombinant Mouse EDA2R Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Met1-Thr138.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product EDA2R Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    Ectodysplasin A2 Receptor (EDA2R)
    Alternative Name
    EDA2R (EDA2R Products)
    Synonyms
    EDA-A2R Protein, EDAA2R Protein, TNFRSF27 Protein, XEDAR Protein, 9430060M22Rik Protein, Xedar Protein, RGD1564025 Protein, ectodysplasin A2 receptor Protein, EDA2R Protein, Eda2r Protein
    Background
    EDA2R is a member of the large family of tumor necrosis factor receptor (TNFR). Previous studies suggested that EDA2R expression might be increased in the kidneys of diabetic mice. High glucose increases EDA2R expression in kidney cells and that EDA2R induces podocyte apoptosis and dedifferentiation in high glucose milieu partially through enhanced ROS generation.
    Molecular Weight
    42.15 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.
    UniProt
    Q8BX35
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