Ectodysplasin A2 Receptor Protein (EDA2R) (AA 1-138) (Fc Tag)
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- Target See all Ectodysplasin A2 Receptor (EDA2R) Proteins
- Ectodysplasin A2 Receptor (EDA2R)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-138
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Ectodysplasin A2 Receptor protein is labelled with Fc Tag.
- Purpose
- Mouse EDA2R Protein
- Sequence
- Met1-Thr138
- Characteristics
- Recombinant Mouse EDA2R Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Met1-Thr138.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product EDA2R Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Ectodysplasin A2 Receptor (EDA2R)
- Alternative Name
- EDA2R (EDA2R Products)
- Synonyms
- EDA-A2R Protein, EDAA2R Protein, TNFRSF27 Protein, XEDAR Protein, 9430060M22Rik Protein, Xedar Protein, RGD1564025 Protein, ectodysplasin A2 receptor Protein, EDA2R Protein, Eda2r Protein
- Background
- EDA2R is a member of the large family of tumor necrosis factor receptor (TNFR). Previous studies suggested that EDA2R expression might be increased in the kidneys of diabetic mice. High glucose increases EDA2R expression in kidney cells and that EDA2R induces podocyte apoptosis and dedifferentiation in high glucose milieu partially through enhanced ROS generation.
- Molecular Weight
- 42.15 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.
- UniProt
- Q8BX35
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