PSG1 Protein (AA 35-419) (His tag)

Catalog No. ABIN5853705

Product Details

Target: PSG1 (Pregnancy Specific beta-1-Glycoprotein 1 (PSG1))

Protein Type: Recombinant

Protein Characteristics: AA 35-419

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This PSG1 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSQVTIEAE PTKVSEGKDV LLLVHNLPQN LTGYIWYKGQ MRDLYHYITS YVVDGEIIIY GPAYSGRETA YSNASLLIQN VTREDAGSYT LHIIKGDDGT RGVTGRFTFT LHLETPKPSI SSSNLNPRET MEAVSLTCDP ETPDASYLWW MNGQSLPMTH SLKLSETNRT LFLLGVTKYT AGPYECEIRN PVSASRSDPV TLNLLPKLPK PYITINNLNP RENKDVLNFT CEPKSENYTY IWWLNGQSLP VSPRVKRPIE NRILILPSVT RNETGPYQCE IRDRYGGIRS DPVTLNVLYG PDLPRIYPSF TYYRSGEVLY LSCSADSNPP AQYSWTINEK FQLPGQKLFI RHITTKHSGL YVCSVRNSAT GKESSKSMTV EVSGKWIP

Purity: > 80 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Denatured

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.4M urea, 10 % glycerol

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: PSG1 (Pregnancy Specific beta-1-Glycoprotein 1 (PSG1))

Alternative Name: PSG1 (PSG1 Products)

Synonyms: B1G1 Protein, CD66f Protein, DHFRP2 Protein, FL-NCA-1/2 Protein, PBG1 Protein, PS-beta-C/D Protein, PS-beta-G-1 Protein, PSBG-1 Protein, PSBG1 Protein, PSG95 Protein, PSGGA Protein, PSGIIA Protein, SP1 Protein, PSG1 Protein, PSG10 Protein, PSG12 Protein, Psg Protein, pregnancy specific beta-1-glycoprotein 1 Protein, pregnancy specific beta-1-glycoprotein 2 Protein, pregnancy specific beta-1-glycoprotein 10, pseudogene Protein, pregnancy-specific beta 1-glycoprotein Protein, PSG1 Protein, PSG2 Protein, PSG10P Protein, Psgb1 Protein

Background: PSG1 belongs to a subgroup of transcription factors that are phosphorylated upon binding to promoter sequences. PSGs are part of the carcinoembryonic antigen (CEA) family and serve as early biochemical markers of syncytiotrophoblast formation. The sequence specificity of DNA binding is conferred by Zn (II) fingers, whereas a different region of PSG1 appears to regulate the affinity of DNA binding. Additionally, PSG1 is believed to mediate placental vascular morphogenesis by enhancing VEGF-A production and endothelial tube formation. Recombinant human PSG1 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Molecular Weight: 45.9kDa (408aa)

NCBI Accession: NP_008836

UniProt: P11464