PSG1 Protein (AA 35-419) (His tag)

Catalog No. ABIN5853705

This Recombinant PSG1 protein is expressed in Escherichia coli (E. coli).

Quick Overview for PSG1 Protein (AA 35-419) (His tag) (ABIN5853705)

Target: PSG1 (Pregnancy Specific beta-1-Glycoprotein 1 (PSG1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 80 %

Product Details

Protein Characteristics: AA 35-419

Purification tag / Conjugate: This PSG1 protein is labelled with His tag.

Sequence: MGSSHHHHHH SSGLVPRGSH MGSQVTIEAE PTKVSEGKDV LLLVHNLPQN LTGYIWYKGQ MRDLYHYITS YVVDGEIIIY GPAYSGRETA YSNASLLIQN VTREDAGSYT LHIIKGDDGT RGVTGRFTFT LHLETPKPSI SSSNLNPRET MEAVSLTCDP ETPDASYLWW MNGQSLPMTH SLKLSETNRT LFLLGVTKYT AGPYECEIRN PVSASRSDPV TLNLLPKLPK PYITINNLNP RENKDVLNFT CEPKSENYTY IWWLNGQSLP VSPRVKRPIE NRILILPSVT RNETGPYQCE IRDRYGGIRS DPVTLNVLYG PDLPRIYPSF TYYRSGEVLY LSCSADSNPP AQYSWTINEK FQLPGQKLFI RHITTKHSGL YVCSVRNSAT GKESSKSMTV EVSGKWIP

Purification: > 80% by SDS-PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Denatured

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M urea, 10 % glycerol

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details

Target: PSG1 (Pregnancy Specific beta-1-Glycoprotein 1 (PSG1))

Alternative Name: PSG1

Background: PSG1 belongs to a subgroup of transcription factors that are phosphorylated upon binding to promoter sequences. PSGs are part of the carcinoembryonic antigen (CEA) family and serve as early biochemical markers of syncytiotrophoblast formation. The sequence specificity of DNA binding is conferred by Zn (II) fingers, whereas a different region of PSG1 appears to regulate the affinity of DNA binding. Additionally, PSG1 is believed to mediate placental vascular morphogenesis by enhancing VEGF-A production and endothelial tube formation. Recombinant human PSG1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Molecular Weight: 45.9 kDa (408aa)

NCBI Accession: NP_008836