RBBP6 Protein (AA 1-313) (His tag)

Catalog No. ABIN5853828

This Recombinant RBBP6 protein is expressed in Escherichia coli (E. coli).

Quick Overview for RBBP6 Protein (AA 1-313) (His tag) (ABIN5853828)

Target: RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 80% by SDS-PAGE

Product Details

Protein Characteristics: AA 1-313

Purification tag / Conjugate: This RBBP6 protein is labelled with His tag.

Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSQSRHR AEAPPLERED SGTFSLGKMI TAKPGKTPIQ VLHEYGMKTK NIPVYECERS DVQIHVPTFT FRVTVGDITC TGEGTSKKLA KHRAAEAAIN ILKANASICF AVPDPLMPDP SKQPKNQLNP IGSLQELAIH HGWRLPEYTL SQEGGPAHKR EYTTICRLES FMETGKGASK KQAKRNAAEK FLAKFSNISP ENHISLTNVV GHSLGCTWHS LRNSPGEKIN LLKRSLLSIP NTDYIQLLSE IAKEQGFNIT YLDIDELSAN GQYQCLAELS TSPITVCHGS GISCGNAQSD AAHNALQYLK IIAERK

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.2M NaCl, 50 % glycerol, 2  mM DTT, 1  mM EDTA

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details

Target: RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))

Alternative Name: PACT

Background: PRKRA is a protein kinase activated by double-stranded RNA which mediates the effects of interferon in response to viral infection. Mutations in this gene have been associated with dystonia. Alternative splicing results in multiple transcript variants. Recombinant human PRKRA protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Molecular Weight: 36.8 kDa (336aa) confirmed by MALDI-TOF

NCBI Accession: NP_003681

UniProt: O75569

Pathways: Regulatory RNA Pathways