RBBP6 Protein (AA 1-313) (His tag)

Catalog No. ABIN7505272

Product Details

Target: RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))

Protein Type: Recombinant

Protein Characteristics: AA 1-313

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This RBBP6 protein is labelled with His tag.

Sequence: Met 1-Lys 313

Characteristics: A DNA sequence encoding the Human PACT protein (O75569) (Met 1-Lys 313) was expressed with a N-His&C-His tag.

Purity: >95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))

Alternative Name: PACT (RBBP6 Products)

Synonyms: MY038 Protein, P2P-R Protein, PACT Protein, RBQ-1 Protein, SNAMA Protein, 4933422O15Rik Protein, AI316869 Protein, BB233631 Protein, C030034J04Rik Protein, C77662 Protein, rbbp6 Protein, MGC75882 Protein, RBBP6 Protein, im:7158869 Protein, rbbp6l Protein, RB binding protein 6, ubiquitin ligase Protein, retinoblastoma binding protein 6, ubiquitin ligase Protein, retinoblastoma binding protein 6 Protein, RBBP6 Protein, Rbbp6 Protein, rbbp6 Protein

Background:

Background: Activates EIF2AK2/PKR in the absence of double stranded RNA (dsRNA), leading to phosphorylation of EIF2S1/EFI2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by DICER1 and for subsequent siRNA-mediated post-t

Synonym: Interferon-inducible double-stranded RNA-dependent protein kinase activator A,PRKRA,PKR-associated protein X

Molecular Weight: 34.32 kDa

UniProt: O75569

Pathways: Regulatory RNA Pathways