SPRED1 Protein (AA 1-444) (His tag)
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- Target See all SPRED1 Proteins
- SPRED1 (Sprouty-Related, EVH1 Domain Containing 1 (SPRED1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-444
- Origin
- Human
- Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SPRED1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMSEETAT SDNDNSYARV RAVVMTRDDS SGGWLPLGGS GLSSVTVFKV PHQEENGCAD FFIRGERLRD KMVVLECMLK KDLIYNKVTP TFHHWKIDDK KFGLTFQSPA DARAFDRGIR RAIEDISQGC PESKNEAEGA DDLQANEEDS SSSLVKDHLF QQETVVTSEP YRSSNIRPSP FEDLNARRVY MQSQANQITF GQPGLDIQSR SMEYVQRQIS KECGSLKSQN RVPLKSIRHV SFQDEDEIVR INPRDILIRR YADYRHPDMW KNDLERDDAD SSIQFSKPDS KKSDYLYSCG DETKLSSPKD SVVFKTQPSS LKIKKSKRRK EDGERSRCVY CQERFNHEEN VRGKCQDAPD PIKRCIYQVS CMLCAESMLY HCMSDSEGDF SDPCSCDTSD DKFCLRWLAL VALSFIVPCM CCYVPLRMCH RCGEACGCCG GKHKAAG
- Purity
- > 80 % by SDS - PAGE
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
-
Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl ( pH 8.0) containing 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- SPRED1 (Sprouty-Related, EVH1 Domain Containing 1 (SPRED1))
- Alternative Name
- SPRED1 (SPRED1 Products)
- Synonyms
- fb14c08 Protein, fj51c03 Protein, zgc:85707 Protein, wu:fb14c08 Protein, wu:fj51c03 Protein, Xspred1 Protein, Xtspred1 Protein, 5730461F13Rik Protein, AL024345 Protein, AW047647 Protein, NFLS Protein, hSpred1 Protein, spred-1 Protein, sprouty-related, EVH1 domain containing 1 Protein, sprouty related EVH1 domain containing 1 Protein, sprouty related, EVH1 domain containing 1 Protein, sprouty related, EVH1 domain containing 1 L homeolog Protein, SPRED1 Protein, sprouty protein with EVH-1 domain 1, related sequence Protein, spred1 Protein, SPRED1 Protein, spred1.L Protein, Bm1_51610 Protein, Spred1 Protein
- Background
- SPRED1 is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. This protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS). Recombinant human SPRED1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 52.9 kDa (467aa)
- NCBI Accession
- NP_689807
- UniProt
- Q7Z699
- Pathways
- Positive Regulation of Response to DNA Damage Stimulus
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