AZGP1 Protein (AA 21-298) (His tag)

Catalog No. ABIN5854487

This Recombinant AZGP1 protein is produced in Baculovirus infected Insect Cells.

Quick Overview for AZGP1 Protein (AA 21-298) (His tag) (ABIN5854487)

Target: AZGP1 (alpha-2-Glycoprotein 1, Zinc-Binding (AZGP1))

Protein Type: Recombinant

Origin: Human

Source: Baculovirus infected Insect Cells

Application: SDS-PAGE (SDS)

Purity: > 95% by SDS-PAGE

Product Details

Protein Characteristics: AA 21-298

Purification tag / Conjugate: This AZGP1 protein is labelled with His tag.

Sequence: QENQDGRYSL TYIYTGLSKH VEDVPAFQAL GSLNDLQFFR YNSKDRKSQP MGLWRQVEGM EDWKQDSQLQ KAREDIFMET LKDIVEYYND SNGSHVLQGR FGCEIENNRS SGAFWKYYYD GKDYIEFNKE IPAWVPFDPA AQITKQKWEA EPVYVQRAKA YLEEECPATL RKYLKYSKNI LDRQDPPSVV VTSHQAPGEK KKLKCLAYDF YPGKIDVHWT RAGEVQEPEL RGDVLHNGNG TYQSWVVVAV PPQDTAPYSC HVQHSSLAQP LVVPWEAS

Endotoxin Level: < 1 EU per 1ug of protein (determined by LAL method)

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details

Target: AZGP1 (alpha-2-Glycoprotein 1, Zinc-Binding (AZGP1))

Alternative Name: ZAG

Background: AZGP1, also known as zinc-alpha-2-glycoprotein, is a member of the MHC class 1 family of proteins. It is reported to associate with PIP (prolactin-inducible protein) but not the MHC light chain, B 2-microglobulin. It is produced by secretory epithelia and is present in most body fluids. It stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. Recombinant human AZGP1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molecular Weight: 33.2 kDa (286aa)

NCBI Accession: NP_001176

UniProt: P25311

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process