AZGP1 Protein (His tag)

Catalog No. ABIN7319195

Product Details

Target: AZGP1 (alpha-2-Glycoprotein 1, Zinc-Binding (AZGP1))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This AZGP1 protein is labelled with His tag.

Purpose: Recombinant Human ZAG/AZGP1 Protein (His Tag)

Sequence: Gln21-Ser298

Characteristics: Recombinant Human Zinc-alhpa-2-Glycoprotein is produced by our Mammalian expression system and the target gene encoding Gln21-Ser298 is expressed with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 7.5.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: AZGP1 (alpha-2-Glycoprotein 1, Zinc-Binding (AZGP1))

Alternative Name: ZAG/AZGP1 (AZGP1 Products)

Synonyms: Zag Protein, ZA2G Protein, ZAG Protein, ZA2GA Protein, Zna2gp Protein, alpha-2-glycoprotein 1, zinc Protein, alpha-2-glycoprotein 1, zinc-binding Protein, Azgp1 Protein, AZGP1 Protein

Background:

Background: Zinc-α-2-Glycoprotein (AZGP1) can be found in blood plasma, seminal plasma, urine, sweat, saliva, liver, and epithelial cells of various human glands. AZGP1 has been proposed in the regulation of body weight, and the melanin production by normal and malignant melanocytes. AZGP1 stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. AZGP1 has been reported to stimulate lipid breakdown and may have an important role in lipid homeostasis. Mature human AZGP1 consists of one MHC class I antigen region and a C2-type Ig-like domain. AZGP1 has two alternate splice forms, one shows a 66 amino acids substitution for the C-terminal 30 amino acids, the other one shows a nine Lys substitution for amino acid 151-298.

Synonym: Zinc-Alpha-2-Glycoprotein, Zn-Alpha-2-GP, Zn-Alpha-2-Glycoprotein, AZGP1, ZAG, ZNGP1

Molecular Weight: 33.2 kDa

UniProt: P25311

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process