PLAUR Protein (AA 23-305) (His tag)

Catalog No. ABIN5854659

Product Details

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Protein Type: Recombinant

Protein Characteristics: AA 23-305

Origin: Human

Source: Baculovirus infected Insect Cells

Purification tag / Conjugate: This PLAUR protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: LRCMQCKTNG DCRVEECALG QDLCRTTIVR LWEEGEELEL VEKSCTHSEK TNRTLSYRTG LKITSLTEVV CGLDLCNQGN SGRAVTYSRS RYLECISCGS SDMSCERGRH QSLQCRSPEE QCLDVVTHWI QEGEEGRPKD DRHLRGCGYL PGCPGSNGFH NNDTFHFLKC CNTTKCNEGP ILELENLPQN GRQCYSCKGN STHGCSSEET FLIDCRGPMN QCLVATGTHE PKNQSYMVRG CATASMCQHA HLGDAFSMNH IDVSCCTKSG CNHPDLDVQY RSGLEHHHHH H

Purity: > 95% by SDS-PAGE

Endotoxin Level: < 1 EU per 1ug of protein (determined by LAL method)

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Alternative Name: uPAR (PLAUR Products)

Background: PLAUR, as known as urokinase plasminogen activator surface receptor isoform 1, is one of two activators that converts the extracellular zymogen plasminogen to plasmin, a serine protease that is involved in a variety of normal and pathological processes that require cell migration and/or tissue destruction. This protein is synthesized and released from cells as a single-chain proenzyme with limited enzymatic activity and is converted to an active two-chain disulfide-linked active enzyme by plasmin and other specific proteinases. Recombinant human PLAUR, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molecular Weight: 32.5 kDa (291aa)

NCBI Accession: NP_002650

UniProt: Q03405

Pathways: Inositol Metabolic Process