CD46 Protein (CD46) (AA 35-313) (His tag)
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- Target See all CD46 Proteins
- CD46
- Protein Type
- Recombinant
- Protein Characteristics
- AA 35-313
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This CD46 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADLCEEPPTF EAMELIGKPK PYYEIGERVD YKCKKGYFYI PPLATHTICD RNHTWLPVSD DACYRETCPY IRDPLNGQAV PANGTYEFGY QMHFICNEGY YLIGEEILYC ELKGSVAIWS GKPPICEKVL CTPPPKIKNG KHTFSEVEVF EYLDAVTYSC DPAPGPDPFS LIGESTIYCG DNSVWSRAAP ECKVVKCRFP VVENGKQISG FGKKFYYKAT VMFECDKGFY LDGSDTIVCD SNSTWDPPVP KCLKGPRPTY KPPVSNYPGY PKPEEGILDS LDHHHHHH
- Purity
- > 90% by SDS-PAGE
- Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product CD46 Protein
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CD46 (CD46) (AA 35-343) protein (His tag)
CD46 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD46 (CD46) (AA 35-329) protein (His tag)CD46 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD46 (CD46) (AA 45-344) protein (His tag)CD46 Origin: Dog Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD46 (CD46) (AA 35-328) protein (His tag)CD46 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
CD46 (CD46) (AA 35-313) protein (His tag)CD46 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
CD46 (CD46) (AA 1-384) protein (GST tag)CD46 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Target
- CD46
- Alternative Name
- CD46 (CD46 Products)
- Background
- CD46, also known as membrane cofactor protein isoform 14, is a type 1 membrane protein that plays an important inhibitory role in the complement system. It is expressed in white blood cells, platelets, epithelial cells, and fibroblasts. The importance of CD46 to complement regulation is underscored by the observation that genetic loss of CD46 leads to development of atypical hemolytic-uremic syndrome, a disease characterized by uncontrolled complement activation. Recombinant human CD46, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 32.5 kDa (288aa)
- NCBI Accession
- NP_758860
- UniProt
- P15529
- Pathways
- Regulation of Actin Filament Polymerization
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