FcRn Protein (AA 22-297) (His tag)
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- Target See all FcRn Proteins
- FcRn (neonatal Fc Receptor (FcRn))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-297
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Origin
- Mouse
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This FcRn protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADPSETRPPL MYHLTAVSNP STGLPSFWAT GWLGPQQYLT YNSLRQEADP CGAWMWENQV SWYWEKETTD LKSKEQLFLE ALKTLEKILN GTYTLQGLLG CELASDNSSV PTAVFALNGE EFMKFNPRIG NWTGEWPETE IVANLWMKQP DAARKESEFL LNSCPERLLG HLERGRRNLE WKEPPSMRLK ARPGNSGSSV LTCAAFSFYP PELKFRFLRN GLASGSGNCS TGPNGDGSFH AWSLLEVKRG DEHHYQCQVE HEGLAQPLTV DLDSSARSSH HHHHH
- Purity
- > 85 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product FcRn Protein
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neonatal Fc Receptor (FcRn) (AA 24-297) protein (His tag)
FcRn Origin: Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
neonatal Fc Receptor (FcRn) (AA 22-297) protein (His tag)FcRn Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
neonatal Fc Receptor (FcRn) (AA 24-297) protein (His tag)FcRn Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
neonatal Fc Receptor (FcRn) (AA 24-297) protein (His-Avi Tag,Biotin)FcRn Origin: Human Host: HEK-293 Cells Recombinant > 95 % by SEC-HPLC SDS, SEC-HPLC, SPR
neonatal Fc Receptor (FcRn) (AA 24-297) protein (His-Avi Tag)FcRn Origin: Human Host: HEK-293 Cells Recombinant > 95 % by SEC-HPLC SDS, SEC-HPLC, SPR
neonatal Fc Receptor (FcRn) (AA 51-160) protein (GST tag)FcRn Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
neonatal Fc Receptor (FcRn) (AA 24-297) (Active) protein (His tag,Strep Tag)FcRn Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
neonatal Fc Receptor (FcRn) (AA 24-297) (Active) protein (His tag,Strep Tag)FcRn Origin: Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
neonatal Fc Receptor (FcRn) (AA 22-297) protein (His tag,Strep Tag)FcRn Origin: Mouse Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
neonatal Fc Receptor (FcRn) (AA 24-297) (Active) protein (His tag,Strep Tag,AVI tag,Biotin)FcRn Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- FcRn (neonatal Fc Receptor (FcRn))
- Alternative Name
- Fcgrt (FcRn Products)
- Background
- Fcgrt, as known as IgG receptor FcRn large subunit p51, is a transmembrane glycoprotein with structural homology to MHC class 1 proteins. This protein is widely expressed in endothelial and epithelial cells and plays an important rloe in IgG homeostasis. Also, it is expessed in neutrophils and myeloid antigen presenting cells. It can enhance IgG-meditated phagocytosis and antigen presentation by heses cells, but it promotes the degradation of opsonizing IgG rather than returning it to the circulation. Recombinant mouse Fcgrt, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 32.1kDa (285aa) 40-57kDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_034319
- UniProt
- Q61559
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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