Ectodysplasin A2 Receptor Protein (EDA2R) (AA 1-138) (hIgG-His-tag)
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- Target See all Ectodysplasin A2 Receptor (EDA2R) Proteins
- Ectodysplasin A2 Receptor (EDA2R)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-138
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This Ectodysplasin A2 Receptor protein is labelled with hIgG-His-tag.
- Application
- SDS-PAGE (SDS)
- Sequence
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MDCQENE YWDQWGRCVT CQRCGPGQEL SKDCGYGEGG DAYCTACPPR RYKSSWGHHR CQSCITCAVI NRVQKVNCTA TSNAVCGDCL PRFYRKTRIG GLQDQECIPC TKQTPTSEVQ CAFQLSLVEA DAPTVPPQEA T - Purity
- > 90% by SDS-PAGE
- Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product EDA2R Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 20 % glycerol, 1 mM DTT.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Target
- Ectodysplasin A2 Receptor (EDA2R)
- Alternative Name
- TNFRSF27/EDA2R (EDA2R Products)
- Background
- EDA2R also known as Tumor necrosis factor receptor superfamily member 27 isoform 2, is a transmembrane protein in the TNF receptor superfamily. This protein itself is strongly associated with androgenetic alopecia (male hair loss). It is widely expressed, notably in embryonic basal epidermal cells and maturing hair follicles. Even though it does not contain a cytoplasmic death domain, it can associate with Fas and induce EDA-A2 dependent apoptosis. Recombinant human EDA2R protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 42.5 kDa (380aa)
- NCBI Accession
- NP_001229239
- UniProt
- Q9HAV5
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