CD84 Protein (CD84) (AA 22-225) (His tag)
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- Target See all CD84 Proteins
- CD84
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-225
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This CD84 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
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KDSEIFT VNGILGESVT FPVNIQEPRQ VKIIAWTSKT SVAYVTPGDS ETAPVVTVTH RNYYERIHAL GPNYNLVISD LRMEDAGDYK ADINTQADPY TTTKRYNLQI YRRLGKPKIT QSLMASVNST CNVTLTCSVE KEEKNVTYNW SPLGEEGNVL QIFQTPEDQE LTYTCTAQNP VSNNSDSISA RQLCADIAMG FRTHHTG - Purity
- > 95% by SDS-PAGE
- Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product CD84 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Target
- CD84
- Alternative Name
- CD84/SLAMF5 (CD84 Products)
- Background
- CD84, also known as slam family member 5 isoform 1, is a self-binding receptor from the CD150 family that is broadly expressed in hematopoietic cells. It is highly expressed in mast cells and that it contributes to the regulation of FCER1 signaling in SAP- and EAT-2-independent and Fes- and Src homology region 2 domain-containing phosphatase-1-dependent mechanisms. It belongs to the signaling lymphocyte activating molecule family of immunoreceptors, and has an unknown function in CLL cells. Its expression is significantly elevated from the early stages of the disease, and is regulated by macrophage migration inhibitory factor and its receptor, CD74. Recombinant human CD84, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 23.8 kDa (213aa)
- NCBI Accession
- NP_001171808
- UniProt
- Q9UIB8
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