IL-31 Protein (AA 24-159) (His tag)

Catalog No. ABIN5854872

This Recombinant IL-31 protein is expressed in Baculovirus infected Insect Cells.

Quick Overview for IL-31 Protein (AA 24-159) (His tag) (ABIN5854872)

Target: IL-31 (IL31) (Interleukin 31 (IL31))

Protein Type: Recombinant

Origin: Dog

Source: Baculovirus infected Insect Cells

Application: SDS-PAGE (SDS)

Purity: > 95 %

Product Details

Protein Characteristics: AA 24-159

Purification tag / Conjugate: This IL-31 protein is labelled with His tag.

Sequence: SHMAPTHQLP PSDVRKIILE LQPLSRGLLE DYQKKETGVP ESNRTLLLCL TSDSQPPRLN SSAILPYFRA IRPLSDKNII DKIIEQLDKL KFQHEPETEI SVPADTFECK SFILTILQQF SACLESVFKS LNSGPQ

Purification: > 95% by SDS-PAGE

Endotoxin Level: < 1 EU per 1ug of protein (determined by LAL method)

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) containing 10 % glycerol

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details

Target: IL-31 (IL31) (Interleukin 31 (IL31))

Alternative Name: IL-31

Background: IL31, also known as interleukin 31, is a member of the gp130/interleukin-6 cytokine family that is produced by cell types such as T helper 2 lymphocytes and cutaneous lymphocyte antigen positive skin homing T cells. IL-31 signals via a heterodimeric receptor complex composed of a gp130 related molecule termed IL-31RA (also GPL and GLMR) and an Oncostatin M receptor (OSM R beta). The IL-31 receptor is constitutively expressed by keratinocytes and upregulated by IFN gamma on monocytes. Recombinant canine IL31, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molecular Weight: 16.1 kDa (142aa)

NCBI Accession: NP_001159386